布莱恩·克罗斯出生于巴塞罗那。他从小就对舞蹈音乐生活产生了浓厚的兴趣，培养出了惊人的音乐制作能力，在西班牙创造了一种围绕他的名字的巨大氛围。他的第一张专辑是在Tempo Music的厂牌下为FRANK TRAX“Alchemy”制作的混音版。在这张混音版之后，他与Tempo Music签订了独家合同，成为该唱片公司的制作人和DJ。在20岁的时候，Brian已经发布了20多首单曲，一直在西班牙的销售排行榜上名列前茅，混音了像Sylver这样的舞蹈乐队“the Smile has left your eyes”。在那之后，混合了另一个对他的工作感兴趣的名字。有一天，世界上最著名的DJ之一阿明·范布伦(Armin van Buuren)被布莱恩·克罗斯(Brian Cross)混音成他最著名的单曲之一“Burned with Desire”。布莱恩逐渐成长为一个制作人，他在其他国家发行了他的单曲，比如墨西哥的Mas Label Music和比利时的AGM Music。2003年，布莱恩与Mar-T和Les Schmitz签约成为健忘症伊比沙岛常驻DJ团队的一员。然后故事就变了。 Brian started to play on the Armada Nights in Amnesia together with Armin van Buuren on Tuesdays during summer time and Sundays together with Robbie Rivera under the JUICY IBIZA nights at Amnesia. Brian signed his single “4U” on Armada Music and he started to collaborate with Armada Music as a producer and DJ. Being part of the Armada DJ's in Ibiza Brian was learning a lot from Paul Oakenfold and Nick Warren, being every time more professional and respected. On 2004 Brian started his Amnesia Ibiza World Tour playing in countries like Canada, Brazil, El Salvador, South Africa, UK, Sweden, Spain, Austria, Poland, Rusia, China, Malaysia, Singapore, Korea, Taiwan, Turkey, Australia and many more countries, starting to be a respected international DJ and producer. 2005 was Brian's year. He created with Amnesia a new compilation series called AMNESIA DJ
